Retinal Degenerative Diseases

PREFACE

ABOUT THE EDITORS

CONTENTS

MOLECULAR GENETICS AND CANDIDATE GENES

GENETIC FACTORS MODIFYING CLINICAL EXPRESSION OF AUTOSOMAL DOMINANT RP

DISEASE-ASSOCIATED VARIANTS OF THE ROD-DERIVED CONE VIABILITY FACTOR ( RdCVF) IN LEBER CONGENITAL AMAUROSIS

LEBER CONGENITAL AMAUROSIS: SURVEY OF THE GENETIC HETEROGENEITY, REFINEMENT OF THE CLINICAL DEFINITION AND PHENOTYPE- GENOTYPE CORRELATIONS AS A STRATEGY FOR MOLECULAR DIAGNOSIS

A FIRST LOCUS FOR ISOLATED AUTOSOMAL RECESSIVE OPTIC ATROPHY ( ROA1) MAPS TO CHROMOSOME 8q21- q22

RCC1-LIKE DOMAIN AND ORF15: ESSENTIALS IN RPGR GENE

CHOROIDAL NEOVASCULARIZATION IN PATIENTS WITH ADULT- ONSET FOVEOMACULAR DYSTROPHY CAUSED BY MUTATIONS IN THE RDS/ PERIPHERIN GENE

BIOCHEMICAL CHARACTERISATION OF THE C1QTNF5 GENE ASSOCIATED WITH LATE- ONSET RETINAL DEGENERATION

BIETTI CRYSTALLINE CORNEORETINAL DYSTROPHY ASSOCIATED WITH CYP4V2 GENE MUTATIONS

DIAGNOSTIC, CLINICAL, CYTOPATHOLOGICAL AND PHYSIOLOGIC ASPECTS OF RETINAL DEGENERATION

FUNDUS APPEARANCE OF CHOROIDEREMIA USING OPTICAL COHERENCE TOMOGRAPY

A2E, A FLUOROPHORE OF RPE LIPOFUSCIN, CAN DESTABILIZE MEMBRANE

AMINO-RETINOID COMPOUNDS IN THE HUMAN RETINAL PIGMENT EPITHELIUM

ANNEXINS IN BRUCH’S MEMBRANE AND DRUSEN

ANIMAL MODELS OF RETINAL DEGENERATION

MOLECULAR MECHANISMS OF PHOTORECEPTOR DEGENERATION IN RP CAUSED BY IMPDH1 MUTATIONS

BIOCHEMICAL FUNCTION OF THE LCA LINKED PROTIEN, ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN LIKE– 1 ( AIPL1)

CHARACTERIZATION OF MOUSE MUTANTS WITH ABNORMAL RPE CELLS

ROD AND CONE PIGMENT REGENERATION IN RPE65-/- MICE

INITIAL OBSERVATIONS OF KEY FEATURES OF AGE- RELATED MACULAR DEGENERATION IN APOE TARGETED REPLACEMENT MICE

ALTERED RHYTHM OF PHOTORECEPTOR OUTER SEGMENT PHAGOCYTOSIS IN b5 INTEGRIN KNOCKOUT MICE

LIGHT/DARK TRANSLOCATION OF ALPHATRANSDUCIN IN MOUSE PHOTORECEPTOR CELLS EXPRESSING G90D MUTANT OPSIN

SLOWED PHOTORESPONSE RECOVERY AND AGE- RELATED DEGENERATION IN CONES LACKING G PROTEIN- COUPLED RECEPTOR KINASE 1

TRANSGENIC ANIMAL STUDIES OF HUMAN RETINAL DISEASE CAUSED BY MUTATIONS IN PERIPHERIN/ RDS

TRANSGENIC EXPRESSION OF LEUKEMIA INHIBITORY FACTOR INHIBITS BOTH ROD AND CONE GENE EXPRESSION

A ROLE FOR BHLH TRANSCRIPTION FACTORS IN RETINAL DEGENERATION AND DYSFUNCTION

CHARACTERISATION OF A MODEL FOR RETINAL NEOVASCULARISATION

A TWO-ALTERNATIVE, FORCED CHOICE METHOD FOR ASSESSING MOUSE VISION

CONDITIONAL GENE KNOCKOUT SYSTEM IN CONE PHOTORECEPTORS

REGULATION OF TIGHT JUNCTION PROTEINS IN CULTURED RETINAL PIGMENT EPITHELIAL CELLS AND IN VEGF OVEREXPRESSING TRANSGENIC MOUSE RETINAS

PATHOLOGICAL HETEROGENEITY OF VASOPROLIFERATIVE RETINOPATHY IN TRANSGENIC MICE OVEREXPRESSING VASCULAR ENDOTHELIAL GROWTH FACTOR IN PHOTORECEPTORS

LASER PHOTOCOAGULATION: OCULAR RESEARCH AND THERAPY IN DIABETIC RETINOPATHY

APPLYING TRANSGENIC ZEBRAFISH TECHNOLOGY TO STUDY THE RETINA

BMI1 LOSS DELAYS PHOTORECEPTOR DEGENERATION IN RD1 MICE

TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL REGULATION OF THE ROD cGMP-PHOSPHODIESTERASE b-SUBUNIT GENE

GENE THERAPY AND NEUROPROTECTION

DOWN-REGULATION OF RHODOPSIN GENE EXPRESSION BY AAV- VECTORED SHORT INTERFERING RNA

ASSESSING THE EFFICACY OF GENE THERAPY IN Rpe65-/- MICE USING PHOTOENTRAINMENT OF CIRCADIAN RHYTHM

LENTIVIRAL VECTORS CONTAINING A RETINAL PIGMENT EPITHELIUM SPECIFIC PROMOTER FOR LEBER CONGENITAL AMAUROSIS GENE THERAPY

GENE DELIVERY TO THE RETINA USING LENTIVIRAL VECTORS

POTENTIAL USE OF CELLULAR PROMOTER(S) TO TARGET RPE IN AAV- MEDIATED DELIVERY

CYTOKINE-INDUCED RETINAL DEGENERATION: ROLE OF SUPPRESSORS OF CYTOKINE SIGNALING ( SOCS) PROTEINS IN PROTECTION OF THE NEURORETINA

DISEASE MECHANISMS AND GENE THERAPY IN A MOUSE MODEL FOR X- LINKED RETINOSCHISIS

MOLECULAR MECHANISMS OF NEUROPROTECTION IN THE EYE

RETINAL DAMAGE CAUSED BY PHOTODYNAMIC THERAPY CAN BE REDUCED USING BDNF

CONTROLLING VASCULAR ENDOTHELIAL GROWTH FACTOR: THERAPIES FOR OCULAR DISEASES ASSOCIATED WITH NEOVASCULARIZATION

INTRAVITREAL INJECTION OF TRIAMCINOLONE ACETONIDE FOR MACULAR EDEMA DUE TO RETINITIS PIGMENTOSA AND OTHER RETINAL DISEASES

CONE SURVIVAL: IDENTIFICATION OF RdCVF

NEUROPROTECTION OF PHOTORECEPTORS IN THE RCS RAT AFTER IMPLANTATION OF A SUBRETINAL IMPLANT IN THE SUPERIOR OR INFERIOR RETINA

GLUTAMATE TRANSPORT MODULATION: A POSSIBLE ROLE IN RETINAL NEUROPROTECTION

ACTIVATION OF CELL SURVIVAL SIGNALS IN THE GOLDFISH RETINAL GANGLION CELLS AFTER OPTIC NERVE INJURY

USHER SYNDROME

ROLES AND INTERACTIONS OF USHER 1 PROTEINS IN THE OUTER RETINA

MOLECULAR ANALYSIS OF THE SUPRAMOLECULAR USHER PROTEIN COMPLEX IN THE RETINA

STEM CELLS, TRANSPLANTATION AND RETINAL REPAIR

LIMITED NEURAL DIFFERENTIATION OF RETINAL PIGMENT EPITHELIUM

RETINAL PIGMENT EPITHELIAL CELLS FROM THERMALLY RESPONSIVE POLYMER- GRAFTED SURFACE REDUCE APOPTOSIS

RETINAL TRANSPLANTATION

MICROARRAY ANALYSIS REVEALS RETINAL STEM CELL CHARACTERISTICS OF THE ADULT HUMAN EYE

USING STEM CELLS TO REPAIR THE DEGENERATE RETINA

OPTIC NERVE REGENERATION: MOLECULAR PRE- REQUISITES AND THE ROLE OF TRAINING

RETINAL GANGLION CELL REMODELLING IN EXPERIMENTAL GLAUCOMA

INDUCED RETINAL DEGENERATIONS

NEURAL PLASTICITY REVEALED BY LIGHT- INDUCED PHOTORECEPTOR LESIONS

FACTORS UNDERLYING CIRCADIAN DEPENDENT SUSCEPTIBILITY TO LIGHT INDUCED RETINAL DAMAGE

SPACE FLIGHT ENVIRONMENT INDUCES DEGENERATION IN THE RETINA OF RAT NEONATES

TOXICITY OF HYPEROXIA TO THE RETINA: EVIDENCE FROM THE MOUSE

TREATMENT WITH CARBONIC ANHYDRASE INHIBITORS DEPRESSES ELECTRORETINOGRAM RESPONSIVENESS IN MICE

INJURY-INDUCED RETINAL GANGLION CELL LOSS IN THE NEONATAL RAT RETINA

BASIC SCIENCE UNDERLYING RETINAL DEGENERATION

ARRESTIN TRANSLOCATION IN ROD PHOTORECEPTORS

BINDING OF N-RETINYLIDENE-PE TO ABCA4 AND A MODEL FOR ITS TRANSPORT ACROSS MEMBRANES

THE CHAPERONE FUNCTION OF THE LCA PROTEIN AIPL1

CRALBP LIGAND AND PROTEIN INTERACTIONS

FUNCTIONAL STUDY OF PHOTORECEPTOR PDEd

LOCALIZATION OF THE INSULIN RECEPTOR AND PHOSPHOINOSITIDE 3- KINASE IN DETERGENT- RESISTANT MEMBRANE RAFTS OF ROD PHOTORECEPTOR OUTER SEGMENTS

MERTK ACTIVATION DURING RPE PHAGOCYTOSIS IN VIVO REQUIRES aVb5 INTEGRIN

PHOTORECEPTOR RETINOL DEHYDROGENASES

PIGMENT EPITHELIUM-DERIVED GROWTH FACTOR INHIBITS FETAL BOVINE SERUM STIMULATED VASCULAR ENDOTHELIAL GROWTH FACTOR SYNTHESIS IN CULTURED HUMAN RETINAL PIGMENT EPITHELIAL CELLS

THE RETINAL PIGMENT EPITHELIUM APICAL MICROVILLI AND RETINAL FUNCTION

UPREGULATION OF TRANSGLUTAMINASE IN THE GOLDFISH RETINA DURING OPTIC NERVE REGENERATION

SURVIVAL SIGNALING IN RETINAL PIGMENT EPITHELIAL CELLS IN RESPONSE TO OXIDATIVE STRESS: SIGNIFICANCE IN RETINAL DEGENERATIONS

INDEX