Pediatric Inflammatory Bowel Disease

Foreword

Preface

Contents

Contributors

Etiology and Pathogenesis

Genetics of Inflammatory Bowel Diseases

Gut Immunity and Inflammatory Bowel Disease

Cytokines and Inflammatory Bowel Disease

Epidemiology and Clinical Features

Epidemiology of Pediatric Inflammatory Bowel Disease

Early Onset Inflammatory Bowel Disease- Epidemiology and Clinical Features

The Natural History of Pediatric Crohn Disease

Natural History of Pediatric Ulcerative Colitis

Natural History of Pediatric Indeterminate Colitis

Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease

Growth Impairment in Pediatric Inflammatory Bowel Disease

Skeletal Health in Pediatric Inflammatory Bowel Disease

Puberty and Pediatric-Onset Inflammatory Bowel Disease

Classification of Pediatric Inflammatory Bowel Disease

Diagnosis

The History and Physical Exam in Pediatric Inflammatory Bowel Disease

Differential Diagnosis of Pediatric Inflammatory Bowel Disease

Laboratory Evaluation of Pediatric Inflammatory Bowel Disease

Radiologic Evaluation of Pediatric Inflammatory Bowel Disease

Endoscopic Modalities in Pediatric Inflammatory Bowel Disease

The Pathology of Chronic Inflammatory Bowel Disease

Video Capsule Endoscopy in Pediatric Inflammatory Bowel Disease

Bone Health Assessment in Pediatric Inflammatory Bowel Disease

Assessment of Growth and Nutritional Status in Pediatric Inflammatory Bowel Disease

Medical Therapy

Pharmacogenetics in Inflammatory Bowel Disease

5-Aminosalicylate Therapy

Antibiotic Therapy

Nutritional Therapy

Probiotic Therapy

Corticosteroid Therapy

6-Mercaptopurine Therapy

Methotrexate Therapy

Infliximab Therapy

Biologic Therapies

Treatment of Perianal Crohn Disease Fistulae

Treatment of Fulminant Colitis

Surgical Therapy

Surgical Management of Crohn’s Disease

Surgical Treatment of Ulcerative Colitis

Pouchitis After Ileal Pouch-Anal Anastomosis

Enteral Feeding Devices and Ostomies

Research

Clinical Indices for Pediatric Inflammatory Bowel Disease Research

Clinical Trials (Clinical Perspective)

Clinical Trials (Industry Perspective)

Special Considerations

Psychological Aspects of Pediatric Inflammatory Bowel Disease

Measurement of Quality of Life in Pediatric Inflammatory Bowel Disease

Irritable Bowel Syndrome and Functional Gastrointestinal Disorders in Pediatric Inflammatory Bowel Disease

Inflammatory Bowel Disease in Pregnancy

Malignant Tumors Arising in Inflammatory Bowel Disease

Quality Improvement in Inflammatory Bowel Disease

Advocacy for Pediatric Patients with Inflammatory Bowel Disease

Legislative Advocacy

Transition from Pediatric to Adult Care

Index