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Optical Polarization in Biomedical Applications
Valery V. Tuchin, Lihong Wang, Dmitry A. Zimnyakov
Verlag Springer-Verlag, 2006
ISBN 9783540453215 , 281 Seiten
Format PDF
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Preface
6
Contents
8
1 Introduction
11
1.1 Light Interaction with Tissues
11
1.2 Definitions of Polarized Light
13
2 Tissue Structure and Optical Models
16
2.1 Introduction
16
2.2 Continuous and Discrete Tissue Models
17
2.3 Scatterer Size Range and Distribution
18
2.4 Refractive-Index Variations and Absorption
20
2.5 Tissue Anisotropy
23
2.6 Volume Fraction and Spatial Ordering of Particles
27
2.7 Eye Tissue Optical Models
29
2.8 Fractal Properties of Tissues and Cell Aggregates
35
2.9 Summary
37
3 Polarized Light Interactions with Weakly Scattering Media
38
3.1 Introduction
38
3.2 Noninteracting Particles
39
3.3 Densely Packed Correlated Particles
45
3.4 Summary
51
4 Polarized Light Interactions with Strongly Scattering Media
53
4.1 Introduction
53
4.2 Multiple Scattering and Radiative Transfer Theory
54
4.3 Monte Carlo Simulation Technique
60
4.4 Densely Packed Particle Systems
69
4.5 Summary
75
5 Polarization Properties of Tissues and Phantoms
76
5.1 Introduction
76
5.2 Light Scattering Matrix Meters
77
5.3 LSM of Thin Tissue and Cell Layers
79
5.4 Strongly Scattering Tissues and Phantoms
84
5.5 Summary
90
6 Polarization-Dependent Interference of Multiply Scattered Light
92
6.1 Introduction
92
6.2 Coherent Backscattering
93
6.3 Polarization-Dependent Temporal Correlations of the Scattered Light
98
6.4 Polarization Microstatistics of Speckles
106
6.5 The Concept of Polarization-Correlation Universality
110
6.6 Summary
117
7 Decay of Light Polarization in Random Multiple Scattering Media
118
7.1 The Similarity in Multiple Scattering of Coherent Light
118
7.2 Influence of Scattering Anisotropy and Scattering Regime
126
7.3 Residual Polarization of Incoherently Backscattered Light
131
7.4 Polarization Decay in Absorbing Media
134
7.5 Summary
145
8 Degree of Polarization in Laser Speckles from Turbid Media
146
8.1 Introduction
146
8.2 Experiments and Simulation
147
8.3 Discussion and Conclusions
153
9 Monte Carlo Modeling of Polarization Propagation in Strongly Scattering Media
155
9.1 Introduction
155
9.2 Method
156
9.3 Results
158
9.4 Summary
165
10 Polarization-Sensitive Optical Coherence Tomography
166
10.1 Introduction
166
10.2 Experimental System: Serial Implementation
167
10.3 Jones Calculus and Mueller Calculus
169
10.4 Experimental System: Parallel Implementation
172
10.5 Experimental Results
177
10.6 Other Implementations
180
10.7 Summary
181
11 Biomedical Diagnostics and Imaging
182
11.1 Introduction
182
11.2 Imaging through Scattering Media and Tissues with Use of Polarized Light
182
11.3 Transillumination Polarization Techniques
186
11.4 Potentialities and Restrictions of Polarization Imaging with Backscattered Light
188
11.5 Polarized Reflectance Spectroscopy of Tissues
196
11.6 Glucose Sensing
197
11.7 Cytometry and Bacteria Sensing
204
11.8 Polarization Microscopy and Tissue Clearing
209
11.9 Digital Photoelastic Analysis
221
11.10 Fluorescence Polarization
223
11.11 Summary
228
A Appendix
229
Single-Scattering Mueller Matrix from Mie Theory
229
Coordinate Transformation in a Multiple Scattering Medium
230
Glossary
233
References
249
Index
283
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