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The Mouse in Biomedical Research - Normative Biology, Husbandry, and Models

James G. Fox, Stephen Barthold, Muriel Davisson, Christian E. Newcomer, Fred W. Quimby, Abigail Smith

 

Verlag Elsevier Reference Monographs, 2006

ISBN 9780080469072 , 816 Seiten

2. Auflage

Format PDF, ePUB, OL

Kopierschutz DRM

Geräte

200,00 EUR


 

Front Cover

1

The Mouse in Biomedical Research: Normative Biology, Husbandry, and Models

4

Copyright Page

5

Table of Contents

6

List of Reviewers

11

List of Contributors

12

Foreword

15

Preface

16

Normative Biology

16

Chapter 1. Gross Anatomy

18

Chapter 2. Mouse Physiology

40

Chapter 3. Reproductive Biology of the Laboratory Mouse

108

Chapter 4. Endocrinology: Bone as a Target Tissue for Hormonal Regulation

140

Chapter 5. Hematology of the Laboratory Mouse

150

Chapter 6. Clinical Chemistry of the Laboratory Mouse

188

Management, Techniques, and Husbandry

188

Chapter 7. Gnotobiotics

234

Chapter 8. Management and Design: Breeding Facilities

252

Chapter 9. Design and Management of Research Facilities for Mice

288

Chapter 10. Nutrition

338

Chapter 11. Health Delivery and Quality Assurance Programs for Mice

402

Chapter 12. Environmental and Equipment Monitoring

426

Chapter 13. Biomethodology and Surgical Techniques

454

Chapter 14. In-Vivo Whole-Body Imaging of the Laboratory Mouse

506

Use of Mice in Biomedical Research

506

Chapter 15. Behavioral Testing

530

Chapter 16. Cardiovascular Disease: Mouse Models of Atherosclerosis

552

Chapter 17. Convulsive Disorders

582

Chapter 18. Eye Research

612

Chapter 19. Genetic Analysis of Rodent Obesity and Diabetes

634

Chapter 20. Mouse Models in Aging Research

654

Chapter 21. Mouse Models of Inherited Human Neurodegenerative Disease

690

Chapter 22. Mouse Skin Ectodermal Organs

708

Chapter 23. Quality Control Testing of Biologics

748

Index

776

Color Plate Section

810