Allergy Frontiers:Classification and Pathomechanisms

Foreword

Preface

Contents

Contributors

Classification and Pathomechanisms

Basic Aspects of Allergy and Hypersensitivity Reactions

Pathogen Recognition and New Insights into Innate Immunity

New Nomenclature and Clinical Aspects of Allergic Diseases

IgE and the High-Affinity Receptor, FceRI: The IgE–CD23 Interaction

Superantigens and Allergic Disease

Immune Complexes: Normal Physiology and Role in Disease

What Is New About Eosinophil Activation in Asthma and Allergic Disease

Mast Cell and Basophils: Interaction with IgE and Responses to Toll like Receptor Activators

T Cells in Allergic Disease

Role of NKT Cells in the Regulation of Ongoing Type 2 Immune Response

CD8+ T Cells Play a Key Role in the Development of Allergic Lung Inflammation

Neutrophils and Their Mediators in Asthma and Allergic Disease

Dendritic Cells, Macrophages and Monocytes in Allergic Disease

Function of Dendritic Cell Subsets in Allergic Disease

Epithelial Cell-Mesenchymal Interaction, Epithelial-Leukocyte Interaction and Epithelial Immune-Response Genes in Allergic Disease

Role of Epidermal Growth Factor Receptor Cascade in Airway Epithelial Regulation of Mucus Production

Epithelial Cell Innate Responses to Rhinovirus Infection

The Role of Platelets in Allergy

Expression and Function of Siglec-8 in Human Eosinophils, Basophils, and Mast Cells1

Effects of Nitric Oxide on Mast Cells: Production, Functions, and Mechanisms of Action

Histamine and Its Receptors

Adenosine: Its Contribution to Our Understanding in Airway Inflammation

Airway Smooth Muscle Dysfunction in Asthma

Genetic Variation in Cytokines, Asthma, and Atopy: The Role of IL-4/IL-13 Pathway Polymorphisms

Allergy and the Bone Marrow: Transmigration Pathways of Hemopoietic Progenitor Cells from the Bone Marrow

Hemopoietic Mechanisms in Allergic Rhinitis and Asthma

Allergy and the Nervous System

Neuroanatomy of the Airways

Biology of Neurotrophins, Neuropeptides, and Muscarinic Receptors in Asthma

Neural Regulation of the Immune Response

Neuroregulation of Mucosal Vasculature

Allergy and Mucosal Immunology

Mucosal Immunity: from Allergy to Coeliac Disease

Mucosa-Associated Lymphoid Tissue and Dynamics of Lymphoid Cells in the Five Different Compartments in Allergic Diseases

Index